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Antikörper

ARHGAP17 Antibody

Produktgrößen
100 ug
£496,00
OAAF04182-100UG
Über dieses Produkt
SKU:
OAAF04182
Zusätzliche Namen:
MST066;MST110;MSTP038;MSTP066;MSTP110;NADRIN;neuron-associated developmentally regulated protein;PP367;PP4534;rho GTPase-activating protein 17;RhoGAP interacting with CIP4 homologs 1;RhoGAP interacting with CIP4 homologs protein 1;rho-type GTPase-activating protein 17;RICH1;RICH-1;WBP15.
Klonalität:
Polyclonal
Weitere Details:
Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42; thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions; possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis; possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
Gendetails:
Rho GTPase activating protein 17
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human RHG17.
Molekulargewicht:
95 kDa
Proteindetails:
Rho GTPase-activating protein 17
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody