EIF3F Antibody
Produktgrößen
100 ug
£496,00
OAAF03658-100UG
Über dieses Produkt
- SKU:
- OAAF03658
- Zusätzliche Namen:
- deubiquitinating enzyme eIF3f;eIF3 p47;eIF3-epsilon;eIF-3-epsilon;eIF3-p47;EIF3S5;Eukaryotic translation initiation factor 3 subunit 5;eukaryotic translation initiation factor 3 subunit F;eukaryotic translation initiation factor 3; subunit 5 (epsilon; 47kD);eukaryotic translation initiation factor 3; subunit 5 epsilon; 47kDa;MRT67.
- Klonalität:
- Polyclonal
- Weitere Details:
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis (PubMed:17581632; PubMed:25849773; PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
- Gendetails:
- eukaryotic translation initiation factor 3 subunit F
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human EIF3F.
- Molekulargewicht:
- 37 kDa
- Proteindetails:
- Eukaryotic translation initiation factor 3 subunit F
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php