DOCK1 Antibody
Produktgrößen
100 ug
£496,00
OAAF03558-100UG
Über dieses Produkt
- SKU:
- OAAF03558
- Zusätzliche Namen:
- 180 kDa protein downstream of CRK;ced5;dedicator of cytokinesis protein 1;DOCK180;DOwnstream of CrK.
- Klonalität:
- Polyclonal
- Weitere Details:
- Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1; mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF); which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).
- Gendetails:
- dedicator of cytokinesis 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DOCK1.
- Molekulargewicht:
- 215 kDa
- Proteindetails:
- Dedicator of cytokinesis protein 1
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php