ATG4A Antibody
Produktgrößen
100 ug
£496,00
OAAF03545-100UG
Über dieses Produkt
- SKU:
- OAAF03545
- Zusätzliche Namen:
- APG4 autophagy 4 homolog A;APG4A;ATG4 autophagy related 4 homolog A;AUTL2;AUT-like 2 cysteine endopeptidase;AUT-like 2; cysteine endopeptidase;autophagin 2;Autophagin-2;autophagy-related cysteine endopeptidase 2;autophagy-related protein 4 homolog A;cysteine protease ATG4A;hAPG4A.
- Klonalität:
- Polyclonal
- Weitere Details:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Gendetails:
- autophagy related 4A cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ATG4A.
- Molekulargewicht:
- 45 kDa
- Proteindetails:
- Cysteine protease ATG4A
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php