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Antikörper

CYP4F2 Antibody

Produktgrößen
100 ug
£496,00
OAAF02964-100UG
Über dieses Produkt
SKU:
OAAF02964
Zusätzliche Namen:
20-HETE synthase;20-hydroxyeicosatetraenoic acid synthase;arachidonic acid omega-hydroxylase;CPF2;CYPIVF2;cytochrome P450 4F2;cytochrome P450; family 4; subfamily F; polypeptide 2;cytochrome P450; subfamily IVF; polypeptide 2;cytochrome P450-LTB-omega;docosahexaenoic acid omega-hydroxylase;leukotriene-B(4) 20-monooxygenase 1;leukotriene-B(4) omega-hydroxylase 1;phylloquinone omega-hydroxylase CYP4F2.
Klonalität:
Polyclonal
Weitere Details:
Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds; including steroids; fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone); and menaquinone-4 (MK-4); a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519; PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney; by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE); possibly influencing blood pressure control (PubMed:10660572; PubMed:17341693; PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B(4) (20-OH LTB4) (PubMed:8026587; PubMed:9799565).
Gendetails:
cytochrome P450 family 4 subfamily F member 2
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human CYP4F2.
Molekulargewicht:
59 kDa
Proteindetails:
Phylloquinone omega-hydroxylase CYP4F2
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody