CARD14 Antibody
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100 ug
£496,00
OAAF02866-100UG
Über dieses Produkt
- SKU:
- OAAF02866
- Zusätzliche Namen:
- bcl10-interacting maguk protein 2;BIMP2;CARD-containing MAGUK protein 2;CARMA2;caspase recruitment domain-containing protein 14;PRP;PSORS2;PSS1.
- Klonalität:
- Polyclonal
- Weitere Details:
- Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1; and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases (PubMed:11278692; PubMed:21302310; PubMed:27113748; PubMed:27071417). May play a role in signaling mediated by TRAF2; TRAF3 and TRAF6 and protects cells against apoptosis.
- Gendetails:
- caspase recruitment domain family member 14
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CAR14.
- Molekulargewicht:
- 113 kDa
- Proteindetails:
- Caspase recruitment domain-containing protein 14
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php