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Antikörper

BCOR Antibody

Produktgrößen
100 ug
£496,00
OAAF02835-100UG
Über dieses Produkt
SKU:
OAAF02835
Zusätzliche Namen:
ANOP2;BCL-6 coreceptor;BCL-6 corepressor;BCL6 interacting corepressor;BCL-6 interacting corepressor;MAA2;MCOPS2.
Klonalität:
Polyclonal
Weitere Details:
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Gendetails:
BCL6 corepressor
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human BCOR.
Molekulargewicht:
192 kDa
Proteindetails:
BCL-6 corepressor
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody