EZH1 Antibody
Produktgrößen
100 ug
£496,00
OAAF02587-100UG
Über dieses Produkt
- SKU:
- OAAF02587
- Zusätzliche Namen:
- enhancer of zeste homolog 1;ENX-2;histone-lysine N-methyltransferase EZH1;KMT6B.
- Klonalität:
- Polyclonal
- Weitere Details:
- Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex; which methylates 'Lys-27' of histone H3; leading to transcriptional repression of the affected target gene. Able to mono-; di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1; H3K27me2 and H3K27me3; respectively. Required for embryonic stem cell derivation and self-renewal; suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes; it is less abundant in embryonic stem cells; has weak methyltransferase activity and plays a less critical role in forming H3K27me3; which is required for embryonic stem cell identity and proper differentiation.
- Gendetails:
- enhancer of zeste 1 polycomb repressive complex 2 subunit
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human EZH1.
- Molekulargewicht:
- 85 kDa
- Proteindetails:
- Histone-lysine N-methyltransferase EZH1
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php