EPHB4 Antibody
Produktgrößen
100 ug
£496,00
OAAF02320-100UG
Über dieses Produkt
- SKU:
- OAAF02320
- Zusätzliche Namen:
- CMAVM2;ephrin receptor EphB4;ephrin type-B receptor 4;hepatoma transmembrane kinase;HFASD;HTK;LMPHM7;MYK1;soluble EPHB4 variant 1;soluble EPHB4 variant 2;soluble EPHB4 variant 3;TYRO11;tyrosine-protein kinase receptor HTK;tyrosine-protein kinase TYRO11.
- Klonalität:
- Polyclonal
- Weitere Details:
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling; morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
- Gendetails:
- EPH receptor B4
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human EPHB4.
- Molekulargewicht:
- 108 kDa
- Proteindetails:
- Ephrin type-B receptor 4
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php