DKC1 Antibody
Produktgrößen
100 ug
£496,00
OAAF02046-100UG
Über dieses Produkt
- SKU:
- OAAF02046
- Zusätzliche Namen:
- CBF5;CBF5 homolog;DKC;DKCX;dyskeratosis congenita 1; dyskerin;Dyskerin;H/ACA ribonucleoprotein complex subunit 4;H/ACA ribonucleoprotein complex subunit DKC1;NAP57;NOLA4;nopp140-associated protein of 57 kDa;nucleolar protein family A member 4;nucleolar protein NAP57;snoRNP protein DKC1;XAP101.
- Klonalität:
- Polyclonal
- Weitere Details:
- Isoform 1: Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex; which catalyzes pseudouridylation of rRNA (PubMed:25219674). This involves the isomerization of uridine such that the ribose is subsequently attached to C5; instead of the normal N1 (PubMed:25219674). Each rRNA can contain up to 100 pseudouridine ('psi') residues; which may serve to stabilize the conformation of rRNAs. Required for ribosome biogenesis and telomere maintenance (PubMed:19179534; PubMed:25219674). Also required for correct processing or intranuclear trafficking of TERC; the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (PubMed:19179534).
- Gendetails:
- dyskerin pseudouridine synthase 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Dyskerin.
- Molekulargewicht:
- 57 kDa
- Proteindetails:
- H/ACA ribonucleoprotein complex subunit DKC1
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php