COPS3 Antibody
Produktgrößen
100 ug
£496,00
OAAF01839-100UG
Über dieses Produkt
- SKU:
- OAAF01839
- Zusätzliche Namen:
- COP9 complex subunit 3;COP9 constitutive photomorphogenic homolog subunit 3;COP9 signalosome complex subunit 3;CSN3;JAB1-containing signalosome subunit 3;SGN3;signalosome subunit 3.
- Klonalität:
- Polyclonal
- Weitere Details:
- Component of the COP9 signalosome complex (CSN); a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes; leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF; CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53; c-jun/JUN; IkappaBalpha/NFKBIA; ITPK1 and IRF8/ICSBP; possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system; respectively.
- Gendetails:
- COP9 signalosome subunit 3
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human JAB1.
- Molekulargewicht:
- 47 kDa
- Proteindetails:
- COP9 signalosome complex subunit 3
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php