E2F6 Antibody
Produktgrößen
100 ug
£496,00
OAAF01781-100UG
Über dieses Produkt
- SKU:
- OAAF01781
- Zusätzliche Namen:
- E2F-6;transcription factor E2F6.
- Klonalität:
- Polyclonal
- Weitere Details:
- Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site; 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
- Gendetails:
- E2F transcription factor 6
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human E2F6.
- Molekulargewicht:
- 31 kDa
- Proteindetails:
- Transcription factor E2F6
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php