E2F4 Antibody
Produktgrößen
100 ug
£496,00
OAAF01780-100UG
Über dieses Produkt
- SKU:
- OAAF01780
- Zusätzliche Namen:
- E2F transcription factor 4; p107/p130-binding;E2F transcription factor 5; p130-binding;E2F-4;E2F-5;p107/p130-binding protein;transcription factor E2F4;transcription factor E2F5.
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site; 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5; binds and activate genes required for centriole biogenesis.|Transcriptional activator that binds to E2F sites; these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5; binds and activate genes required for centriole biogenesis.
- Gendetails:
- E2F transcription factor 4|E2F transcription factor 5
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human E2F4.
- Isotyp:
- IgG
- Molekulargewicht:
- 43 kDa
- Proteindetails:
- Transcription factor E2F4|Transcription factor E2F5
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php