FOXO3 Antibody
Produktgrößen
100 ug
£496,00
OAAF01485-100UG
Über dieses Produkt
- SKU:
- OAAF01485
- Zusätzliche Namen:
- AF6q21;AF6q21 protein;FKHRL1;FKHRL1P2;forkhead box O3A;forkhead box protein O3;forkhead homolog (rhabdomyosarcoma) like 1;forkhead in rhabdomyosarcoma-like 1;forkhead; Drosophila; homolog of; in rhabdomyosarcoma-like 1;FOXO2;FOXO3A;FOXO3A-.
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcriptional activator which triggers apoptosis in the absence of survival factors; including neuronal cell death upon oxidative stress (PubMed:10102273; PubMed:16751106). Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882). Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5; promotes induction of miR-34b and miR-34c expression; 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (PubMed:21329882). In response to metabolic stress; translocates into the mitochondria where it promotes mtDNA transcription (PubMed:23283301).
- Gendetails:
- forkhead box O3
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human FOXO3A.
- Molekulargewicht:
- 71 kDa
- Proteindetails:
- Forkhead box protein O3
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php