CDKN1B Antibody
Produktgrößen
100 ug
£496,00
OAAF01395-100UG
Über dieses Produkt
- SKU:
- OAAF01395
- Zusätzliche Namen:
- CDKN4;cyclin-dependent kinase inhibitor 1B;cyclin-dependent kinase inhibitor 1B (p27; Kip1);Cyclin-dependent kinase inhibitor p27;KIP1;MEN1B;MEN4;P27KIP1.
- Klonalität:
- Polyclonal
- Weitere Details:
- Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A; but has little inhibitory activity on CDK2 bound to SPDYA (PubMed:28666995). Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly; stability; and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
- Gendetails:
- cyclin dependent kinase inhibitor 1B
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human p27 Kip1.
- Isotyp:
- IgG
- Molekulargewicht:
- 22 kda
- Proteindetails:
- Cyclin-dependent kinase inhibitor 1B
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php