CASR Antibody
Produktgrößen
100 ug
£496,00
OAAF00973-100UG
Über dieses Produkt
- SKU:
- OAAF00973
- Zusätzliche Namen:
- CAR;EIG8;extracellular calcium-sensing receptor;FHH;FIH;GPRC2A;hCasR;HHC;HHC1;HYPOC1;NSHPT;parathyroid Ca(2+)-sensing receptor 1;parathyroid cell calcium-sensing receptor 1;PCAR1.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (PubMed:7759551; PubMed:8702647; PubMed:8636323; PubMed:8878438; PubMed:17555508; PubMed:19789209; PubMed:21566075; PubMed:22114145; PubMed:23966241; PubMed:25292184; PubMed:25104082; PubMed:26386835; PubMed:25766501; PubMed:22789683). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:7759551). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids; such as Trp or Phe; act concertedly with divalent cations; such as calcium or magnesium; to achieve full receptor activation (PubMed:27434672; PubMed:27386547).
- Gendetails:
- calcium sensing receptor
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor.
- Isotyp:
- IgG
- Molekulargewicht:
- 120 kDa
- Proteindetails:
- Extracellular calcium-sensing receptor
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php