FOS Antibody
Produktgrößen
100 ug
£496,00
OAAF00734-100UG
Über dieses Produkt
- SKU:
- OAAF00734
- Zusätzliche Namen:
- activator protein 1;AP-1;cellular oncogene c-fos;Cellular oncogene fos;C-FOS;FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS);FBJ murine osteosarcoma viral oncogene homolog;Fos proto-oncogene; AP-1 trancription factor subunit;G0/G1 switch regulatory protein 7;p55;proto-oncogene c-Fos.
- Klonalität:
- Polyclonal
- Weitere Details:
- Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer; FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation; forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction; cell proliferation and differentiation. In growing cells; activates phospholipid synthesis; possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
- Gendetails:
- Fos proto-oncogene; AP-1 transcription factor subunit
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Fos.
- Isotyp:
- IgG
- Molekulargewicht:
- 40 kDa
- Proteindetails:
- Proto-oncogene c-Fos
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php