CDH5 Antibody
Produktgrößen
100 ug
£496,00
OAAF00512-100UG
Über dieses Produkt
- SKU:
- OAAF00512
- Zusätzliche Namen:
- 7B4;7B4 antigen;cadherin 5; type 2 (vascular endothelium);cadherin 5; type 2; VE-cadherin (vascular epithelium);cadherin-5;CD144;cd144 antigen;endothelial-specific cadherin;vascular endothelial cadherin;VE-cadherin.
- Klonalität:
- Polyclonal
- Weitere Details:
- Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ; PARD3; TIAM1 and RAP1B to the cell junction.
- Gendetails:
- cadherin 5
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human VE-Cadherin around the phosphorylation site of Tyr731.
- Molekulargewicht:
- 87 kDa
- Proteindetails:
- Cadherin-5
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php