DDR1 Antibody
Produktgrößen
100 ug
£496,00
OAAF00504-100UG
Über dieses Produkt
- SKU:
- OAAF00504
- Zusätzliche Namen:
- CAK;CD167;CD167 antigen-like family member A;cell adhesion kinase;DDR;Discoidin receptor tyrosine kinase;EDDR1;epithelial discoidin domain-containing receptor 1;HGK2;mammary carcinoma kinase 10;MCK10;NEP;neuroepithelial tyrosine kinase;neurotrophic tyrosine kinase; receptor; type 4;NTRK4;Protein-tyrosine kinase 3A;protein-tyrosine kinase RTK-6;PTK3;PTK3A;PTK3A protein tyrosine kinase 3A;RTK6;TRK E;TRKE;tyrosine kinase DDR;tyrosine-protein kinase CAK.
- Klonalität:
- Polyclonal
- Weitere Details:
- Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix; remodeling of the extracellular matrix; cell migration; differentiation; survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2; MMP7 and MMP9; and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy; for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration; and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
- Gendetails:
- discoidin domain receptor tyrosine kinase 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DDR1 around the phosphorylation site of Tyr513.
- Molekulargewicht:
- 101 kDa
- Proteindetails:
- Epithelial discoidin domain-containing receptor 1
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php