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Antikörper

CSNK1G2 Antibody

Produktgrößen
100 ug
£496,00
OAAF00438-100UG
Über dieses Produkt
SKU:
OAAF00438
Zusätzliche Namen:
casein kinase I;casein kinase I isoform gamma-1;casein kinase I isoform gamma-2;casein kinase I isoform gamma-3;CK1g2;CK1gamma1;CKI-gamma 2;CKI-gamma 3;CSNK1G3L.
Klonalität:
Polyclonal
Weitere Details:
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT; MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation; thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex; thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.|Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).|Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN.
Gendetails:
casein kinase 1 gamma 1|casein kinase 1 gamma 2|casein kinase 1 gamma 3
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263.
Molekulargewicht:
48 kDa
Proteindetails:
Casein kinase I isoform gamma-1|Casein kinase I isoform gamma-2|Casein kinase I isoform gamma-3
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody