GRIA2 Antibody
Produktgrößen
100 ug
£474,00
OAAF00328-100UG
Über dieses Produkt
- SKU:
- OAAF00328
- Zusätzliche Namen:
- AMPA-selective glutamate receptor 2;GluA2;gluR-2;GLUR2;gluR-B;GLURB;GluR-K2;glutamate receptor 2;Glutamate receptor ionotropic; AMPA 2;glutamate receptor; ionotropic; AMPA 2;HBGR2;NEDLIB.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change; leading to the opening of the cation channel; and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state; characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8; shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Through complex formation with NSG1; GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).
- Gendetails:
- glutamate ionotropic receptor AMPA type subunit 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GluR2 around the phosphorylation site of Ser880.
- Isotyp:
- IgG
- Molekulargewicht:
- 98 kDa
- Proteindetails:
- Glutamate receptor 2
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php