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Antikörper

AR Antibody

Produktgrößen
100 ug
£496,00
OAAF00137-100UG
Über dieses Produkt
SKU:
OAAF00137
Zusätzliche Namen:
AIS;androgen receptor;AR8;DHTR;dihydrotestosterone receptor;HUMARA;HYSP1;KD;NR3C4;nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;TFM.
Klonalität:
Polyclonal
Weitere Details:
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849). Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes; negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). Transcription activation is also down-regulated by NR0B2. Activated; but not phosphorylated; by HIPK3 and ZIPK/DAPK3.
Gendetails:
androgen receptor
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human Androgen Receptor around the phosphorylation site of Ser94.
Molekulargewicht:
98 kDa
Proteindetails:
Androgen receptor
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody