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Antikörper

GCG Antibody

Produktgrößen
0.1ml
£522,00
OAAD00393-0.1ML
Über dieses Produkt
SKU:
OAAD00393
Zusätzliche Namen:
GLP1; GLP2; GRPP; GLP-1
translate.label.attr.clone:
2F9
Klonalität:
Monoclonal
Weitere Details:
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these; glucagon; is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation.
Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms.
Finally; the fourth peptide is similar to glicentin; an active enteroglucagon.Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1; GLP-2; oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.
Host:
Mouse
Immunogen:
Purified recombinant fragment of human GCG expressed in E. Coli.
Isotyp:
IgG1
Molekulargewicht:
21kDa
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4C; for long term storage; store at -20C.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody