CTCF Antibody
Produktgrößen
0.1ml
£522,00
OAAD00392-0.1ML
Über dieses Produkt
- SKU:
- OAAD00392
- Zusätzliche Namen:
- MRD21; FAP108; CFAP108
- translate.label.attr.clone:
- 1D11
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site; the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)- containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element; it can block communication between enhancers and upstream promoters; thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers; prostate cancers; and Wilms' tumors.Tissue specificity: Ubiquitous.
Absent in primary spermatocytes. - Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of human CTCF expressed in E. Coli.
- Isotyp:
- IgG1
- Molekulargewicht:
- 83kDa
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php