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Antikörper

CD86 Antibody

Produktgrößen
0.1ml
£522,00
OAAD00377-0.1ML
Über dieses Produkt
SKU:
OAAD00377
Zusätzliche Namen:
B70; B7-2; B7.2; LAB72; CD28LG2
translate.label.attr.clone:
1B3
Klonalität:
Monoclonal
Weitere Details:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells; and it is the ligand for two proteins at the cell surface of T cells; CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described; but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.
Host:
Mouse
Immunogen:
Purified recombinant fragment of human CD86 expressed in E. Coli.
Isotyp:
IgG1
Molekulargewicht:
52kDa
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4C; for long term storage; store at -20C.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody