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Antikörper

CDC27 Antibody

Produktgrößen
0.1ml
£522,00
OAAD00368-0.1ML
Über dieses Produkt
SKU:
OAAD00368
Zusätzliche Namen:
APC3; HNUC; NUC2; H-NUC; ANAPC3; CDC27Hs; D0S1430E; D17S978E
translate.label.attr.clone:
5C12
Klonalität:
Monoclonal
Weitere Details:
Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27; and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC); which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat); a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2; p55CDC and BUBR1; and thus may be involved in controlling the timing of mitosis.
Host:
Mouse
Immunogen:
Purified recombinant fragment of human CDC27 expressed in E. Coli.
Isotyp:
IgG1
Molekulargewicht:
91kDa
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4C; for long term storage; store at -20C.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody