CDKN1B Antibody
Produktgrößen
0.1ml
£522,00
OAAD00359-0.1ML
Über dieses Produkt
- SKU:
- OAAD00359
- Zusätzliche Namen:
- KIP1; MEN4; CDKN4; MEN1B; P27KIP1
- translate.label.attr.clone:
- 3D8
- Klonalität:
- Monoclonal
- Weitere Details:
- p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene; and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. Decreased levels of p27Kip1; mainly due to proteosomal degradation; are found in various epithelial tumors originating from lung; breast; colon; ovary; esophagus; thyroid and prostate.Tissue specificity: Expressed in all tissues tested.
Highest levels in skeletal muscle; lowest in liver and kidney. - Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of human CDKN1B expressed in E. Coli.
- Isotyp:
- IgG1
- Molekulargewicht:
- 22kDa
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php