FLT1 Antibody
Produktgrößen
0.1ml
£522,00
OAAD00323-0.1ML
Über dieses Produkt
- SKU:
- OAAD00323
- Zusätzliche Namen:
- FLT; FLT-1; VEGFR1; VEGFR-1
- translate.label.attr.clone:
- 3D10
- Klonalität:
- Monoclonal
- Weitere Details:
- Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); also known as FLT1 or VEGFR-1. It is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains; a transmembrane segment; and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A; VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells; placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened; soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
- Host:
- Mouse
- Immunogen:
- Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.
- Isotyp:
- IgG1
- Molekulargewicht:
- 100kDa
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php