FGFR1 Antibody
Produktgrößen
0.1ml
£522,00
OAAD00313-0.1ML
Über dieses Produkt
- SKU:
- OAAD00313
- Zusätzliche Namen:
- CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1
- translate.label.attr.clone:
- 3D4F7
- Klonalität:
- Monoclonal
- Weitere Details:
- Fibroblast growth factor receptor 1 (FGFR1); also known as basic fibroblast growth factor receptor 1; fms-related tyrosine kinase-2 / Pfeiffer syndrome; and CD331; is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family; where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
- Host:
- Mouse
- Immunogen:
- Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.
- Isotyp:
- IgG2b
- Molekulargewicht:
- 92kDa
- Proteindetails:
- Fibroblast growth factor receptor 1
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php