CD45 Antibody
Produktgrößen
0.1ml
£522,00
OAAD00292-0.1ML
Über dieses Produkt
- SKU:
- OAAD00292
- Zusätzliche Namen:
- LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
- translate.label.attr.clone:
- 4A8A4C7A2
- Klonalität:
- Monoclonal
- Weitere Details:
- CD45; also known as TPRC(protein tyrosine phosphatase; receptor type; C). The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported.
- Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of CD45 expressed in E. Coli.
- Isotyp:
- IgG1
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php