F8 Antibody
Produktgrößen
0.1ml
£522,00
OAAD00282-0.1ML
Über dieses Produkt
- SKU:
- OAAD00282
- Zusätzliche Namen:
- AHF; F8B; F8C; HEMA; FVIII; DXS1253E
- translate.label.attr.clone:
- 5E9B2
- Klonalität:
- Monoclonal
- Weitere Details:
- F8: coagulation factor VIII; procoagulant component. This gene encodes coagulation factor VIII; which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which; in the presence of Ca+2 and phospholipids; converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein; isoform a; which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein; isoform b; which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A; a common recessive X-linked coagulation disorder.
- Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of F8 expressed in E. Coli.
- Isotyp:
- IgG1
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php