FGFR4 Antibody
Produktgrößen
0.1ml
£522,00
OAAD00248-0.1ML
Über dieses Produkt
- SKU:
- OAAD00248
- Zusätzliche Namen:
- TKF; JTK2; CD334
- translate.label.attr.clone:
- 4H2B10B2
- Klonalität:
- Monoclonal
- Weitere Details:
- FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. There are four members of the FGF receptor family: FGFR-1 (flg); FGFR-2 (bek; KGFR); FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain; a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization; the receptors are phosphorylated at specific tyrosine residues. These receptor proteins play a role in important processes such as cell division; regulating cell growth and maturation; formation of blood vessels; wound healing; and embryo development. Although specific functions of FGFR4 remain unclear; studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.
- Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of FGFR4 expressed in E. Coli.
- Isotyp:
- IgG1
- Molekulargewicht:
- 88kDa
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php