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Antikörper

EPHB4 Antibody

Produktgrößen
0.1ml
£500,00
OAAD00239-0.1ML
Über dieses Produkt
SKU:
OAAD00239
Zusätzliche Namen:
HTK; MYK1; HFASD; CMAVM2; LMPHM7; TYRO11
translate.label.attr.clone:
5B8F7
Klonalität:
Monoclonal
Weitere Details:
EPH receptor B4 (EphB4); with 987-amino acid protein (about 108kDa); belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands; the ephrins; regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation; switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy.
Host:
Mouse
Immunogen:
Purified recombinant fragment of EphB4 expressed in E. Coli.
Isotyp:
IgG2a
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4C; for long term storage; store at -20C.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody