ER-ALPHA Antibody
Produktgrößen
0.1mg
£500,00
OAAD00234-0.1MG
Über dieses Produkt
- SKU:
- OAAD00234
- Zusätzliche Namen:
- ER; ESR; Era; ESRA; ESTRR; NR3A1
- translate.label.attr.clone:
- 2B7
- Klonalität:
- Monoclonal
- Weitere Details:
- The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding; DNA binding; and activation of transcription. Alternative splicing results in several ER mRNA transcripts; which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER; ERA and ER-beta; occur; each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary; ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles; interstitial gland; and germinal epithelium cells. Nuclear staining for ERA occurred in thecal; interstitial gland; and germinal epithelium cells. In the uterus; strong ERA immunoreactivity was detected in nuclei of epithelial; stromal; and muscle cells.
- Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. Coli.
- Isotyp:
- IgG1
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C; for long term storage; store at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php