DYSTROPHIN Antibody
Produktgrößen
100 ug
£431,00
OAAD00151-100UG
Über dieses Produkt
- SKU:
- OAAD00151
- Zusätzliche Namen:
- BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
- translate.label.attr.clone:
- DYS-48
- Klonalität:
- Monoclonal
- Weitere Details:
- Dystrophin(DMD) gene has 79 exons spanning at least 2; 300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved; alternatively spliced region of the gene.
beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons; the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb; and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain.
overexpression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects. - Host:
- Mouse
- Immunogen:
- Recombinant human dystrophin fragment.
- Isotyp:
- IgG2b
- Proteindetails:
- Dystrophin
- Aufreinigung:
- Purified by the goat anti-mouse IgG Affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20C for one year. After reconstitution; at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php