C-MYC Antibody
Produktgrößen
100 ug
£431,00
OAAD00143-100UG
Über dieses Produkt
- SKU:
- OAAD00143
- Zusätzliche Namen:
- MRTL; MYCC; c-Myc; bHLHe39
- translate.label.attr.clone:
- IMD-3
- Klonalität:
- Monoclonal
- Weitere Details:
- C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization; and to a lesser extent the transformation of cells; in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division; and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein.
- Isotyp:
- IgG2a
- Proteindetails:
- Myc proto-oncogene protein
- Aufreinigung:
- Purified by the goat anti-mouse IgG Affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- At -20C for one year. After reconstitution; at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php