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Antikörper

CASP9 Antibody

Produktgrößen
100ul
£615,00
OAAB20976-100UL
Über dieses Produkt
SKU:
OAAB20976
Zusätzliche Namen:
MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
Klonalität:
Monoclonal
Weitere Details:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome; a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Gendetails:
caspase 9
Host:
Rabbit
Molekulargewicht:
46 kDa
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody