BRCC3 Antibody - N-terminal region
Produktgrößen
200ul
£597,00
OAAB20949-200UL
Über dieses Produkt
- SKU:
- OAAB20949
- Zusätzliche Namen:
- C6.1A; BRCC36; CXorf53
- translate.label.attr.clone:
- RB53911
- Klonalität:
- Polyclonal
- Konzentration:
- 500 ug/mL
- Weitere Details:
- This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC); which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response; where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains; and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya; a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.
- Gendetails:
- BRCA1/BRCA2-containing complex subunit 3
- Host:
- Rabbit
- Immunogen:
- This BRCC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 18-50 amino acids from human BRCC3.
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 36 kDa
- Aufreinigung:
- Protein A column purification; followed by peptide affinity purification
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php