ARID1A Antibody - C-terminal region
Produktgrößen
200ul
£597,00
OAAB20885-200UL
Über dieses Produkt
- SKU:
- OAAB20885
- Zusätzliche Namen:
- ELD; B120; CSS2; OSA1; P270; hELD; BM029; MRD14; hOSA1; BAF250; C1orf4; BAF250a; SMARCF1
- translate.label.attr.clone:
- RB53540
- Klonalität:
- Polyclonal
- Konzentration:
- 500 ug/mL
- Weitere Details:
- This gene encodes a member of the SWI/SNF family; whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI; which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First; it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second; the C-terminal of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- AT-rich interaction domain 1A
- Host:
- Rabbit
- Immunogen:
- This ARID1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1717-1750 amino acids from human ARID1A.
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 242 kDa
- Aufreinigung:
- Protein A column purification; followed by peptide affinity purification
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php