Epha1 Antibody - N-terminal region
Produktgrößen
400ul
£615,00
OAAB18889-400UL
Über dieses Produkt
- SKU:
- OAAB18889
- Zusätzliche Namen:
- Ep; Es; Eph; Esk; AL033318; 5730453L17Rik
- Klonalität:
- Polyclonal
- Weitere Details:
- Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
- Host:
- Rabbit
- Immunogen:
- This Mouse Epha1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 70-105 amino acids from the N-terminal region of Mouse Epha1.
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 109 kDa
- Aufreinigung:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php