Ephb4 Antibody - C-terminal region
Produktgrößen
400ul
£615,00
OAAB18855-400UL
Über dieses Produkt
- SKU:
- OAAB18855
- Zusätzliche Namen:
- Htk; MDK2; Myk1; Tyro; Tyro11; AI042935; b2b2412C; b2b2412Clo
- Klonalität:
- Polyclonal
- Weitere Details:
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4- mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling; morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
- Host:
- Rabbit
- Immunogen:
- This Mouse Ephb4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 889-923 amino acids from the C-terminal region of Mouse Ephb4.
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 109 kDa
- Aufreinigung:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php