DDR1 Antibody
Produktgrößen
400ul
£630,00
OAAB18681-400UL
Über dieses Produkt
- SKU:
- OAAB18681
- Zusätzliche Namen:
- CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A
- translate.label.attr.clone:
- 1464CT339.1.54
- Klonalität:
- Monoclonal
- Weitere Details:
- Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix; remodeling of the extracellular matrix; cell migration; differentiation; survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2; MMP7 and MMP9; and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy; for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration; and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
- Host:
- Mouse
- Immunogen:
- This DDR1 antibody is generated from a mouse immunized with a recombinant protein.
- Isotyp:
- IgG2b; k
- Molekulargewicht:
- 101 kDa
- Aufreinigung:
- This antibody is purified through a protein G column; followed by dialysis against PBS.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php