COPS3 Antibody
Produktgrößen
100ul
£597,00
OAAB18373-100UL
Über dieses Produkt
- SKU:
- OAAB18373
- Zusätzliche Namen:
- CSN3; SGN3
- Klonalität:
- Polyclonal
- Weitere Details:
- Component of the COP9 signalosome complex (CSN); a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes; leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF; CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53; c-jun/JUN; IkappaBalpha/NFKBIA; ITPK1 and IRF8/ICSBP; possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system; respectively.
- Host:
- Rabbit
- Isotyp:
- Rabbit Ig
- Molekulargewicht:
- 48 kDa
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php