DDR1 Antibody - N-terminal region
Produktgrößen
400ul
£597,00
OAAB17175-400UL
Über dieses Produkt
- SKU:
- OAAB17175
- Zusätzliche Namen:
- CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A
- Klonalität:
- Polyclonal
- Konzentration:
- Varies by lot. See vial for concentration.
- Weitere Details:
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth; differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells; particularly in the kidney; lung; gastrointestinal tract; and brain. In addition; this protein is significantly over-expressed in several human tumors from breast; ovarian; esophageal; and pediatric brain. The gene is located on chromosome 6p21.3 in proximity to several HLA class I genes.
- Host:
- Rabbit
- Immunogen:
- This DDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human DDR1.
- Isotyp:
- Ig
- Molekulargewicht:
- 101 kDa
- Proteindetails:
- Epithelial discoidin domain-containing receptor 1
- Aufreinigung:
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php