FLT3
Produktgrößen
400ul
£597,00
OAAB17159-400UL
Über dieses Produkt
- SKU:
- OAAB17159
- Zusätzliche Namen:
- FLK2; STK1; CD135; FLK-2
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor; generally the g phosphate of ATP; onto an acceptor amino acid in a substrate protein. By this basic mechanism; protein kinases mediate most of the signal transduction in eukaryotic cells; regulating cellular metabolism; transcription; cell cycle progression; cytoskeletal rearrangement and cell movement; apoptosis; and differentiation. With more than 500 gene products; the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation; adhesion; motility and death. There are currently about 90 TK genes sequenced; 58 are of receptor protein TK (e.g. EGFR; EPH; FGFR; PDGFR; TRK; and VEGFR families); and 32 of cytosolic TK (e.g. ABL; FAK; JAK; and SRC families).
- Host:
- Rabbit
- Immunogen:
- This FLT3 (CD135) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-64 amino acids from the N-terminal region of human FLT3 (CD135).
- Isotyp:
- Ig
- Molekulargewicht:
- 113 kDa
- Proteindetails:
- Receptor-type tyrosine-protein kinase FLT3
- Aufreinigung:
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php