CrkRS Antibody - N-terminal region
Produktgrößen
400ul
£597,00
OAAB17095-400UL
Über dieses Produkt
- SKU:
- OAAB17095
- Zusätzliche Namen:
- CRK7; CRKR; CRKRS
- Klonalität:
- Polyclonal
- Weitere Details:
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor; generally the g phosphate of ATP; onto an acceptor amino acid in a substrate protein. By this basic mechanism; protein kinases mediate most of the signal transduction in eukaryotic cells; regulating cellular metabolism; transcription; cell cycle progression; cytoskeletal rearrangement and cell movement; apoptosis; and differentiation. With more than 500 gene products; the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7; 11; 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K; Ste11/MAP3K; and Ste20/MAP4K). MAP kinase cascades; consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
- Host:
- Rabbit
- Immunogen:
- This CrkRS (CRK7) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CrkRS (CRK7).
- Isotyp:
- Ig
- Molekulargewicht:
- 164155 Da
- Proteindetails:
- Cyclin-dependent kinase 12
- Aufreinigung:
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php