GREMLIN Antibody - C-terminal region
Produktgrößen
400ul
£615,00
OAAB16489-400UL
Über dieses Produkt
- SKU:
- OAAB16489
- Zusätzliche Namen:
- Dr; ld; Drm; gre; Grem; Cktsf1b; Cktsf1b1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.45 mg/ml
- Weitere Details:
- GREMLIN is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs; BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists; to which this gene belongs; is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP; this gene may play a role in regulating organogenesis; body patterning; and tissue differentiation. In mouse; this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth.
- Host:
- Rabbit
- Immunogen:
- This GREMLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the C-terminal region of mouse GREMLIN.
- Isotyp:
- IgG
- Molekulargewicht:
- 21 kDa
- Proteindetails:
- Gremlin-1
- Aufreinigung:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php