GJB2 Antibody - C-terminal region
Produktgrößen
400ul
£597,00
OAAB11368-400UL
Über dieses Produkt
- SKU:
- OAAB11368
- Zusätzliche Namen:
- HID; KID; PPK; BAPS; CX26; DFNA3; DFNB1; NSRD1; DFNA3A; DFNB1A
- Klonalität:
- Polyclonal
- Konzentration:
- 2 mg/ml
- Weitere Details:
- Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules; including ions; metabolic intermediates; and second messengers; and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits; which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Immunohistochemical staining of human cochlear cells demonstrated high levels of GJB2 expression. Mutations in GJB2 are associated with genetically derived hearing impairments; including autosomal recessive nonsyndromic deafness.
- Host:
- Rabbit
- Immunogen:
- This GJB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-226 amino acids from the C-terminal region of human GJB2.
- Isotyp:
- Ig
- Molekulargewicht:
- 26 kDa
- Proteindetails:
- Gap junction beta-2 protein
- Aufreinigung:
- This antibody is purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php