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Antikörper

COL1A1 Antibody - C-terminal region

Produktgrößen
400ul
£615,00
OAAB10798-400UL
Über dieses Produkt
SKU:
OAAB10798
Zusätzliche Namen:
OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml (Actual concentration varies with each lot)
Weitere Details:
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone; cornea; dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV; Ehlers-Danlos syndrome type VIIA; Ehlers-Danlos syndrome Classical type; Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22; where this gene and the gene for platelet-derived growth factor beta are located; are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans; resulting from unregulated expression of the growth factor. Two transcripts; resulting from the use of alternate polyadenylation signals; have been identified for this gene. [provided by R. Dalgleish].
Host:
Rabbit
Immunogen:
This COL1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1077-1106 amino acids from the C-terminal region of human COL1A1.
Isotyp:
Ig
Molekulargewicht:
139 kDa
Proteindetails:
Collagen alpha-1(I) chain
Aufreinigung:
This antibody is purified through a protein A column; followed by peptide affinity purification.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody