FOLH1 Antibody - N-terminal region
Produktgrößen
400ul
£597,00
OAAB10007-400UL
Über dieses Produkt
- SKU:
- OAAB10007
- Zusätzliche Namen:
- PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1; NAALAdase
- Klonalität:
- Polyclonal
- Konzentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Weitere Details:
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates; including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate; central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates; resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
- Host:
- Rabbit
- Immunogen:
- This FOLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the N-terminal region of human FOLH1.
- Isotyp:
- Ig
- Molekulargewicht:
- 84331 Da
- Proteindetails:
- Glutamate carboxypeptidase 2
- Aufreinigung:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php